Characterization and manipulation of Corticothalamic neurons in associative cortices using Syt6-Cre transgenic mice.

Vaasjo LO, Han X, Thurmon AN, Tiemroth AS, Berndt H, Korn M, Figueroa A, Reyes R, Feliciano-Ramos PA, Galazo MJ.

Journal of Comparative Neurology 2022 May;530(7):1020-1048.

doi: 10.1002/cne.25256. Epub 2021 Oct 23. PMID: 34617601.

Deregulated Rac1 Activity in Neural Crest Controls Cell Proliferation, Migration and Differentiation During Midbrain Development.

Gahankari A, Dong C, Bartoletti G, Galazo M, He F.

Front Cell Dev Biol. 2021 Sep 7;9:704769. doi: 10.3389/fcell.2021.704769. PMID: 34557485; PMCID: PMC8452869.

Transient callosal projections of L4 neurons are eliminated for the acquisition of local connectivity

De León Reyes NS, Mederos S, Varela I, Weiss LA, Perea G, Galazo MJ, Nieto M. . Nat Commun. 2019 Oct 7;10(1):4549. doi: 10.1038/s41467-019-12495-w. PMID: 31591398; PMCID: PMC6779895.

Rodriguez-Muela N, Litterman NK, Norabuena EM, Mull JL, Galazo MJ, Sun C, Ng SY, Makhortova NR, White A, Lynes MM, Chung WK, Davidow LS, Macklis JD, Rubin LL. Single-Cell Analysis of SMN Reveals Its Broader Role in Neuromuscular Disease. Cell Rep. 2017 Feb 7;18(6):1484-1498. doi: 10.1016/j.celrep.2017.01.035. PMID: 28178525; PMCID: PMC5463539.

Galazo MJ, Emsley JG, Macklis JD. Corticothalamic Projection Neuron Development beyond Subtype Specification: Fog2 and Intersectional Controls Regulate Intraclass Neuronal Diversity. Neuron. 2016 Jul 6;91(1):90-106. doi: 10.1016/j.neuron.2016.05.024. Epub 2016 Jun 16. PMID: 27321927; PMCID: PMC5094453.

Greig LC, Woodworth MB, Galazo MJ, Padmanabhan H, Macklis JD. Molecular logic of neocortical projection neuron specification, development and diversity. Nat Rev Neurosci. 2013 Nov;14(11):755-69. doi: 10.1038/nrn3586. Epub 2013 Oct 9. PMID: 24105342; PMCID: PMC3876965.

Jabaudon D, Shnider SJ, Tischfield DJ, Galazo MJ, Macklis JD. RORβ induces barrel-like neuronal clusters in the developing neocortex. Cereb Cortex. 2012 May;22(5):996-1006. doi: 10.1093/cercor/bhr182. Epub 2011 Jul 28. PMID: 21799210; PMCID: PMC3328343.

Rubio-Garrido P, Pérez-de-Manzo F, Porrero C, Galazo MJ, Clascá F. Thalamic input to distal apical dendrites in neocortical layer 1 is massive and highly convergent. Cereb Cortex. 2009 Oct;19(10):2380-95. doi: 10.1093/cercor/bhn259. Epub 2009 Feb 2. PMID: 19188274.

Clascá F, Rubio-Garrido P, Galazo MJ, Porrero C. Nuevas perspectivas anatomofuncionales sobre las redes talamocorticales [Diversity in thalamic relay neurons: evidence for "bottom-up" and "top-down" information flow in thalamocortical pathways]. An R Acad Nac Med (Madr). 2009;126(3):357-72; discussion 372-3. Spanish. PMID: 20432677.

Galazo MJ, Martinez-Cerdeño V, Porrero C, Clascá F. Embryonic and postnatal development of the layer I-directed ("matrix") thalamocortical system in the rat. Cereb Cortex. 2008 Feb;18(2):344-63. doi: 10.1093/cercor/bhm059. Epub 2007 May 20. PMID: 17517678.

Ramos-Moreno T, Galazo MJ, Porrero C, Martínez-Cerdeño V, Clascá F. Extracellular matrix molecules and synaptic plasticity: immunomapping of intracellular and secreted Reelin in the adult rat brain. Eur J Neurosci. 2006 Jan;23(2):401-22. doi: 10.1111/j.1460-9568.2005.04567.x. PMID: 16420448.

Martínez-Cerdeño V, Galazo MJ, Clascá F. Reelin-immunoreactive neurons, axons, and neuropil in the adult ferret brain: evidence for axonal secretion of reelin in long axonal pathways. J Comp Neurol. 2003 Aug 11;463(1):92-116. doi: 10.1002/cne.10748. PMID: 12811805.

Martínez-Cerdeño V, Galazo MJ, Cavada C, Clascá F. Reelin immunoreactivity in the adult primate brain: intracellular localization in projecting and local circuit neurons of the cerebral cortex, hippocampus and subcortical regions. Cereb Cortex. 2002 Dec;12(12):1298-311. doi: 10.1093/cercor/12.12.1298. PMID: 12427680.

miR-193b-365 microcluster downstream of Fezf2 coordinates neuron-subtype identity and dendritic morphology in cortical projection neurons.

iScience 2024 Nov 28;27 (12):111500.  Asha Iyer *, Lee O Vaasjo*, Verl B Siththanandan, Rajan K C , Abbigail Thurmon, Mauren Akumuo, Victoria Lu, Chelsea Nnebe, Ramesh Nair, Maria J Galazo#, Suzanne Tharin.

(* co-first authors, #Corresponding author)

Zmiz1 is a novel regulator of brain development associated with autism and intellectual disability.

K C R, Tiemroth AS, Thurmon AN, Meadows SM, Galazo MJ. Front Psychiatry. 2024 Apr 15;15:1375492. doi: 10.3389/fpsyt.2024.1375492. PMID: 38686122; PMCID: PMC11057416.

Mapping dynamic molecular changes in hippocampal subregions after traumatic brain injury through spatial proteomics.

Clin Proteomics. 2024 May 12;21(1):32. Sudipa Maity, Yuanyu Huang, Mitchell D Kilgore, Abbigail N Thurmon, Lee O Vaasjo, Maria J Galazo, Xiaojiang Xu, Jing Cao, Xiaoying Wang, Bo Ning, Ning Liu, Jia Fan.

doi: 10.1186/s12014-024-09485-6.

Symmetry in levels of axon-axon homophilic adhesion establishes topography in the corpus callosum and development of connectivity between brain hemispheres.

Alexandros Poulopoulos, Patrick Davis, Cheryl Brandenburg, Yasuhiro Itoh, Maria J Galazo, Luciano C Greig, Andrea J Romanowski, Bogdan Budnik, Jeffrey D Macklis.

bioRxiv. 2024 Mar 31:2024.03.28.587108.

doi: 10.1101/2024.03.28.587108.

Tle4 controls both developmental acquisition and early post-natal maturation of corticothalamic projection neuron identity

Galazo MJ, Sweetser DA, Macklis JD. . Cell Rep. 2023 Aug 9;42(8):112957. doi: 10.1016/j.celrep.2023.112957. Epub ahead of print. PMID: 37561632.

Hippocampal memory reactivation during sleep is correlated with specific cortical states of the retrosplenial and prefrontal cortices.

Feliciano-Ramos PA, Galazo M, Penagos H, Wilson M.

Learning and Memory. 2023 Sep 27;30(9):221-236. doi: 10.1101/lm.053834.123. PMID: 37758288; PMCID: PMC10547389.